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HBO and The Ringer's Bill Simmons hosts the most downloaded sports podcast of all time, with a rotating crew of celebrities, athletes, and media staples, as well as mainstays like Cousin Sal, Joe House, and a slew of other friends and family members who always happen to be suspiciously available.
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Latest Breakthroughs in Longevity Research with Aubrey de Grey
In this episode, Jacob Watson Howland interviews Aubrey de Grey about recent advancements in longevity research. Emphasizing research in mice, de Grey discusses various interventions such as rapamycin, heterochronic bone marrow transplants, telomerase gene therapy, and senescent cell removal. De Grey explains the significance of these methods and the surprising effects they have on lifespan extension, despite the complexity of aging processes. He highlights the importance of starting experiments in middle-aged mice for better relatability and details the costs and potential of further research in this field.
00:00 Introduction to Longevity Research
00:43 The Importance of Lifespan Measurement
01:20 Recent Breakthroughs in Longevity
01:53 Multi-Intervention Experiments
03:04 Challenges and Costs of Longevity Experiments
03:30 Key Interventions in Longevity
06:22 Understanding Senescent Cells
98 episodes
