In this comprehensive episode, we combine our earlier discussions on beta-blocker overdose and calcium channel blocker overdose into one high-yield comparison. These are two of the most dangerous cardiovascular toxicities encountered in emergency medicine and critical care.

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👉 You’ll learn: Mechanisms of toxicity (β-receptor blockade vs calcium channel blockade) Symptoms & clinical findings: bradycardia, hypotension, seizures, bronchospasm, pulmonary edema Diagnostic pearls: hypoglycemia in beta-blocker toxicity vs hyperglycemia in calcium channel blocker toxicity Stepwise treatment: airway, IV fluids, atropine, glucagon, calcium, high-dose insulin euglycemia therapy (HIET), vasopressors, lipid emulsion, pacing, and ECMO Unique features: lipophilic beta blockers causing CNS depression, verapamil causing profound cardiogenic shock

Link to video: https://www.youtube.com/watch?v=WunW6SY1kc4

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