Pulse Pressure Variation (PPV) is one of the most reliable bedside tools for assessing fluid responsiveness in mechanically ventilated ICU patients. Unlike static measures such as CVP, PPV uses arterial waveform analysis to predict whether a patient will benefit from fluids.

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In this episode, we cover: What PPV is and the physiology behind it 🫀 Step-by-step method to calculate PPV from the arterial line 🧮 Clinical thresholds: ≥13%, ≤9%, and the “gray zone” 📊 The tidal volume challenge and adjunct tests (PLR, mini-fluid challenge) Strengths, pitfalls, and when PPV is unreliable ⚠️ Evidence from meta-analyses and sepsis guidelines A quick bedside algorithm for real-world use 🔀 3 board-style practice questions (beginner to advanced) 📝

Link to video:https://www.youtube.com/watch?v=hgBYp7U6skY

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