Andrew Ng on June 16, 2025 at AI Startup School in San Francisco.Andrew Ng has helped shape some of the most influential movements in modern AI—from online education to deep learning to AI entrepreneurship. In this talk, he shares what he’s learning now: why execution speed matters more than ever, how agentic workflows are changing what startups can build, and why concreteness beats vagueness when turning ideas into products. He reflects on the rise of AI coding assistants, the shifting bottlenecks in product development, and why, despite faster software, it’s still human judgment and responsibility that will shape what comes next.…

François Chollet on June 16, 2025 at AI Startup School in San Francisco. François Chollet is a leading voice in AI. He's the creator of the Keras library, author of Deep Learning with Python, and the founder of the ARC Prize, a global competition aimed at measuring true general intelligence. He's spent years thinking deeply about what intelligence actually is—and why scaling up today’s AI models isn’t enough to reach it. In this talk, he walks through the limits of pretraining and memorized skills, and lays out a path toward true general intelligence—AI that can adapt on the fly, reason in new situations, and invent novel solutions. He explains why abstraction and compositionality matter, how ARC became the benchmark for progress, and what his team at a new research lab called Ndea is building next.…

A fireside with Dr. Fei-Fei Li on June 16, 2025 at AI Startup School in San Francisco.Dr. Fei-Fei Li is often called the godmother of AI—and for good reason. Before the world had AI as we know it, she was helping build the foundation.In this fireside, she recounts the creation of ImageNet, a project that helped ignite the deep learning revolution by providing the data backbone modern computer vision needed. She walks through the early belief in data-driven methods, the shock of seeing convolutional networks outperform expectations in 2012, and how those breakthroughs led to captioning, storytelling, and ultimately, generative models.Now, she’s taking on one of AI’s hardest frontiers: spatial intelligence. Fei-Fei shares why modeling the 3D world is essential for AGI—and why it may be even more difficult than language.…

Kirsten Green, founder of Forerunner Ventures, has backed some of the most iconic consumer brands of the past two decades — from Warby Parker to Chime to Dollar Shave Club. In this conversation with Garry, she shares how great products (not marketing tricks) still win, why AI is unlocking a new kind of emotional relationship between consumers and technology, and what founders can learn from the messy creative stage we're in right now. She also breaks down how shifts in distribution, wellness, and digital behavior are reshaping what it means to build for real human needs.…

A fireside with Satya Nadella on June 17, 2025 at AI Startup School in San Francisco.Satya Nadella started at Microsoft in 1992 as an engineer. Three decades later, he’s now Chairman & CEO, navigating the company through one of the most profound technological shifts yet: the rise of AI.In this conversation, he shares how Microsoft is thinking about this moment— from the infrastructure needed to train frontier models, to the social permission required to use that compute. He draws parallels to the early PC and internet eras, breaks down what makes a great team, and reflects on what he’d build if he were starting his career today.…

A fireside with Sam Altman at AI Startup School in San Francisco.Sam Altman grew up obsessed with technology, broke into the Stanford mainframe as a kid, and dropped out to start his first company before turning 20.In this conversation, he traces the path from early startup struggles to building OpenAI—sharing what he’s learned about ambition, the weight of responsibility, and how to keep building when the whole world is watching. He opens up about the hardest moments of his career, the limits of personal productivity, and why, in the end, it's all still about finding people you like working with and doing something that matters.…

A fireside with Elon Musk at AI Startup School in San Francisco.Before rockets and robots, Elon Musk was drilling holes through his office floor to borrow internet. In this candid talk, he walks through the early days of Zip2, the Falcon 1 launches that nearly ended SpaceX, and the “miracle” of Tesla surviving 2008. He shares the thinking that guided him—building from first principles, doing useful things, and the belief that we’re in the middle of an intelligence big bang.…

Andrej Karpathy's keynote at AI Startup School in San Francisco.Drawing on his work at Stanford, OpenAI, and Tesla, Andrej sees a shift underway. Software is changing, again. We’ve entered the era of “Software 3.0,” where natural language becomes the new programming interface and models do the rest.He explores what this shift means for developers, users, and the design of software itself— that we're not just using new tools, but building a new kind of computer. Slides provided by Andrej: https://drive.google.com/file/d/1a0h1mkwfmV2PlekxDN8isMrDA5evc4wW/view?usp=sharing…

Michael Truell, co-founder and CEO of Anysphere, the company behind Cursor, joins Garry to talk about building one of the fastest-growing startups of all time—and why he's betting on a future beyond code. He walks through the early insights that led his team to leave a promising AI-powered CAD project and instead chase a bigger dream: reinventing how software is written. From years of false starts and rewrites to Cursor's breakthrough moment, Michael explains what it takes to build a tool that could eventually replace programming as we know it. He also reflects on their first 10 hires, why taste still matters and how the decade ahead will unlock a new kind of creativity for builders everywhere.…

Fusion may still sound like science fiction— but it might not be for much longer. With AI pushing demand for clean power to new highs, a breakthrough may finally be close. For Decoded, YC General Partner Gustaf Alstromer traces the history of fusion, the physics behind it, and the engineering challenges that stalled it for nearly a century. He also looks at how Helion is approaching the problem differently, as they develop a new fusion system expected to deliver power to Microsoft by 2028.…

In this episode of The Breakdown, Tom and Dave are joined by fellow YC General Partner Pete Koomen to lay out a new vision for how AI should actually work: not as a chatbot bolted onto legacy software, but as a customizable tool that helps people offload the work they don't want to do. From editable system prompts to agents that act more like collaborators, they dig into what it means to build AI-native software—and why the future belongs to products that let users teach machines how to think.…

Coding agents are no longer a distant idea—they're already starting to reshape how we work. YC's Tom Blomfield and David Lieb discuss how AI coding tools are transforming software development, why small, high-agency teams will be able to do what once took armies of engineers, and why there's never been a better time to start something new. They explore the bigger picture too: a future where there's abundance, knowledge work becomes more accessible, and founders have more leverage than ever before. If you're thinking about building, there's no better moment than right now.…

AI can't yet one-shot an entire product—but with the rise of vibe coding, it's getting close. YC's Tom Blomfield has spent the last month building side projects with tools like Claude Code, Windsurf, and Aqua, seeing just how far you can push modern LLMs. From writing full-stack apps to debugging with a single paste of an error message, AI is becoming a legit collaborator in the dev process. This is a playbook for anyone who wants to get the most out of vibe coding and build faster.…

Imagine ordering groceries and having them show up at your doorstep in just 10 minutes. That’s the promise of Zepto, the fastest-growing e-commerce company in India. In this episode of How To Build The Future, Garry sits down with Aadit Palicha, the co-founder and CEO of Zepto, to discuss how they got started in a Whatsapp group, what it’s like going up against incumbents like Amazon and Zomato and how the future of e-commerce is changing in the age of intelligence.…

Not long ago, America led the world in building and innovation. But over the past 50 years, bureaucracy and red tape have made it nearly impossible to get big things done. Still, there’s a growing movement to turn that around — to build faster, smarter, and better than ever before. In this episode of The Main Function, Garry sits down with Atlantic staff writer and Plain English podcast host Derek Thompson to discuss his new book Abundance (co-authored with Ezra Klein). They discuss how we got here, what needs fixing, and what a bold, more prosperous 2050 could look like.…