Articles from the medical literature are digested, abstracted, and discussed by our AI hosts, with topics in symptom management, diagnosis, ethics and others.
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EthicsDoc Podcasts

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017 - Suzetrigine - a non-opioid, non-NSAID sodium channel blocker for pain
16:23
16:23
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16:23Questions? Comments? Send us a message! In this episode we discuss suzetrigine, a novel, non-opioid pain medication that specifically targets the NaV1.8 sodium channel to manage acute pain. The document explores its pharmacological mechanisms, highlighting how it blocks pain signals without causing the addictive or severe side effects associated wi…
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016 - Hypertrophic Pulmonary Osteoarthropathy in Palliative Medicine
19:29
19:29
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19:29Questions? Comments? Send us a message! This episode examines Hypertrophic Pulmonary Osteoarthropathy (HPO), a rare syndrome often associated with underlying pulmonary malignancies. It outlines HPO's clinical presentation, which includes digital clubbing and painful, swollen joints, emphasizing the importance of differentiating it from metastatic b…
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015 - Ethics: A Mother in Jeopardy: The Ethics of Pregnancy and Chemotherapy
17:17
17:17
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17:17Questions? Comments? Send us a message! In this episode, we discuss a complex ethical dilemma concerning a pregnant woman diagnosed with advanced ovarian cancer who refuses recommended termination and chemotherapy due to prior fertility struggles. Several experts in medicine, ethics, law, spiritual care, and social work provide differing perspectiv…
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014 - Symptom Management: Botulinum Toxin for Post Thoracotomy Pain Syndrome
19:06
19:06
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19:06Questions? Comments? Send us a message! This case report explores the use of botulinum toxin type A (BTX-A) injections for treating post-thoracotomy pain syndrome (PTPS), a chronic neuropathic condition affecting many patients after thoracotomy. The study highlights that traditional treatments often fail to provide adequate relief, prompting invest…
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013 - Symptom Management: Dronabinol for Neuropathic Pain
18:22
18:22
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18:22Questions? Comments? Send us a message! I. Introduction This briefing document synthesizes key findings from several sources exploring the potential of cannabinoids in managing neuropathic pain. The sources include pre-clinical investigations, clinical trial reviews, and decision analysis models, offering a multifaceted view of the topic. We will e…
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012 - Symptom Management: Gabapentin for Intractable Hiccups
15:32
15:32
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15:32Questions? Comments? Send us a message! Hiccups, while often seen as a minor inconvenience, can become a significant health issue when they are persistent or intractable. This episode explores the science behind hiccups, their potential medical causes, and treatment options, particularly the use of gabapentin as an off-label solution. • Discussion …
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011 - Diagnostics: Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) - An easily missed diagnosis in palliative medicine
10:15
10:15
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10:15Questions? Comments? Send us a message! This case report details a patient with chronic lymphocytic leukemia whose initially misdiagnosed joint pain was ultimately attributed to the rare syndrome of remitting seronegative symmetrical synovitis with pitting edema (RS3PE). The report discusses RS3PE's characteristics, often overlooked due to its rari…
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010 - Data: Palliative Medicine Consultation and Hospital Readmissions
12:03
12:03
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12:03Questions? Comments? Send us a message! This retrospective study from a 21-hospital system analyzed the effect of palliative medicine consultations on 30-day hospital readmission rates for patients with six diagnoses (heart failure, sepsis, pneumonia, COPD, AMI, and stroke). The research found statistically significant reductions in readmissions fo…
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009 - Ethics: Life Support after Brain Death
21:02
21:02
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21:02Questions? Comments? Send us a message! This article presents an ethics case study concerning a 52-year-old male declared brain dead, whose family refuses to remove life support. Multiple perspectives—medical, nursing, chaplain, social work, legal, and ethical—are offered, exploring the conflict between the family's emotional denial of death and th…
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008 - Diagnostics: Post-radiation Lichen Planus
14:44
14:44
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14:44Questions? Comments? Send us a message! This case report details a rare instance of post-radiation lichen planus in a 64-year-old male, following radiation therapy for squamous cell carcinoma. The report examines the patient's medical history, clinical presentation, and treatment response to topical triamcinolone. The authors review existing litera…
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007 - Diagnostics: Posterior Reversible Encephalopathy Syndrome (PRES) - Don't Miss This Diagnosis!
13:49
13:49
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13:49Questions? Comments? Send us a message! This case report and accompanying discussion detail Posterior Reversible Encephalopathy Syndrome (PRES), a neurological condition presenting with seizures, visual disturbances, and altered mental status. Often misdiagnosed as more severe conditions like intracranial hemorrhage, PRES demonstrates reversible br…
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006 - Symptom Management: BJR Method for Methadone Conversion
16:05
16:05
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16:05Questions? Comments? Send us a message! The BJR method is a novel mathematical approach to methadone conversion that aims to improve upon existing methods by providing a smoother, less discontinuous, and less linear output for a reasonable and safe methadone dose. Here's how it improves upon existing conversion approaches: Addresses Limitations of …
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005 - Cultural: The Therapeutic Baptism : A Case of Missed Cultural Cues in a Terminally Ill Patient
27:27
27:27
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27:27Questions? Comments? Send us a message! The case study underscores the potential for misinterpreting spiritual distress as psychiatric illness, resulting in inappropriate treatment. Clinicians should learn several key lessons from the case of Mr. G, primarily emphasizing the importance of addressing patients' spiritual needs alongside their physica…
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004 - Ethics: Suicide and Self Determination - what are the limits to autonomy when a patient lacks capacity?
26:27
26:27
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26:27Questions? Comments? Send us a message! This ethics roundtable discussion centers on the case of JG, a 45-year-old man who attempted suicide and subsequently suffered severe brain damage. The article presents differing perspectives from medical, nursing, risk management, ethics, pastoral, social work, and legal professionals regarding the ethical i…
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002 - Ethics: Surrogacy, Religious Beliefs, and Medical Treatment
23:28
23:28
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23:28Questions? Comments? Send us a message! Ethical and legal considerations surrounding a comatose Jehovah's Witness patient's need for a life-saving blood transfusion are debated. The patient's parents, also Jehovah's Witnesses, refuse consent, while her brother advocates for the transfusion, claiming she wasn't a practicing member. The case highligh…
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003 - Ethics: State-Erected Barriers to End-of-Life Care
11:05
11:05
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11:05Questions? Comments? Send us a message! This ethics roundtable discussion analyzes a case study where a patient's daughter-in-law, the primary caregiver, seeks to withdraw life support, but state law restricts surrogacy to blood relatives or spouses. The discussion explores the ethical and legal implications of this restrictive law, highlighting th…
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001 - Ethics: Surrogate Decision Making at End of Life
20:40
20:40
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20:40Questions? Comments? Send us a message! Who makes the decision if the patient lacks capacity? Multiple healthcare professionals offer varying perspectives on the ethical and legal dilemma surrounding the care of a 93-year-old comatose patient (JH). A conflict exists between JH's legally appointed Power of Attorney (POA), his hired caregiver, who wa…
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