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Hiccups, while often seen as a minor inconvenience, can become a significant health issue when they are persistent or intractable. This episode explores the science behind hiccups, their potential medical causes, and treatment options, particularly the use of gabapentin as an off-label solution.
• Discussion of the three types of hiccups: acute, persistent, and intractable
• Explanation of the hiccup reflex arc and its neurological basis
• Overview of the myriad causes of intractable hiccups, including central nervous system and psychological factors
• Introduction and definition of gabapentin, including its off-label use for hiccups
• Presentation of case studies demonstrating the efficacy of gabapentin
• Examination of potential side effects of gabapentin relative to other treatments
• Alternatives to gabapentin, including other medications and non-pharmacological home remedies
• Ethical considerations regarding off-label prescriptions and open communication with doctors

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