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This case report explores the use of botulinum toxin type A (BTX-A) injections for treating post-thoracotomy pain syndrome (PTPS), a chronic neuropathic condition affecting many patients after thoracotomy. The study highlights that traditional treatments often fail to provide adequate relief, prompting investigation into alternative therapies. BTX-A's mechanism, which involves reducing inflammation and peripheral neurotransmitters, suggests a potential benefit for localized pain syndromes like PTPS. Prior studies indicate the effectiveness of BTX-A in managing other neuropathic pain conditions such as trigeminal neuralgia and diabetic neuropathy. The case report details a successful instance where subcutaneous BTX-A injections significantly alleviated PTPS symptoms, allowing the patient to discontinue opioid medications. While the treatment appears promising and carries minimal risk, the authors suggest that further clinical trials should be conducted.

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