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Daniel Engel Podcasts

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Big Brains

University of Chicago Podcast Network

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Big Brains explores the groundbreaking research and discoveries that are changing our world. In each episode, we talk to leading experts and unpack their work in straightforward terms. Interesting conversations that cover a gamut of topics from how music affects our brains to what happens after we die.
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Royal Grown Radio

Royal Grown Radio

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Royal Grown Radio is a cultivation and cannabis focused podcast with guests from leading Cultivators, Brands, Advocates, and Professionals from Humboldt county and beyond. Hosted by Michael Beck and Rick Elliott of Royal Gold Soils
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POWER Players

POWER Productions

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POWER Players is the podcast for high-performers hungry for real, unfiltered conversations with today’s most dynamic business minds. Each episode pulls back the curtain on the raw, often untold journeys of successful entrepreneurs, executives, and innovators who aren’t just building companies, but are actively building legacies! This isn’t your surface-level success story. POWER Players dives deep into the pivotal moments, calculated risks, and hard-earned lessons that shaped each guest’s ri ...
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Join Vanessa Fukunaga, Owner, President | CEO of Engel & Völkers Snell Real Estate and Ocean Blue World as she invites the movers and shakers around the world for epic conversations on how they are topping the luxury market and using their craft, talent and influence to propose positive change and expansion. Learn, laugh and be entertained with discussions on real estate, lifestyle, health, travel, architecture, fashion, beauty, technology, and absolutely e-v-e-r-y-t-h-i-n-g that move the bu ...
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Welcome to Trading Places, the extremely terrible, very bad podcast on VC secondaries. Hosts Dave McClure and Aman Verjee unpack the biggest news in venture capital, late-stage funding, crypto valuations, and this week's explosive valuation corner on why Grayscale's IPO might be heading for disaster. This Thanksgiving episode dives deep into Michae…
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Episode 13 of @TradingPlacesPod featuring Emily Zheng (@Pitchbook) is out now! Welcome to Trading Places, the extremely terrible, very bad podcast on VC secondaries. Hosts Dave McClure and Aman Verjee (with special guest Amber filling in) break down the biggest news in venture secondaries, late-stage funding rounds, market dynamics, and this week's…
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Can you imagine a world in which a wearable device, like a smartwatch, could move your fingers to strum the guitar or play the drums? That kind of technology is part of the innovative research coming out of the Human-Computer Integration Lab at the University of Chicago, led by renowned computer scientist Pedro Lopes. His lab is developing a new ge…
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Episode 12 of the @TradingPlacesPod featuring Sean Engel from Top Tier Capital Partners is out now! This week: Are we in an AI bubble (again)? Data center capacity constraints meet infinite hyperscaler ambition, SoftBank sells Nvidia (again!) to bet on OpenAI, and venture secondaries are the new must-have strategy for every LP trying to escape the …
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Episode 11 of the Trading Places Podcast featuring Daniel Blake from UI Charitable is out now! This week: the IRS as your secret secondary buyer, donor-advised fund (DAF) strategies that turn illiquid assets into tax savings, and the wild world of prediction markets—where Polymarket and Kalshi are coming for DraftKings’ and FanDuel’s lunch money. T…
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More and more women in the United States are saying no to motherhood. In 2023, the U.S. fertility rate reached the lowest number on record. But the idea of non-motherhood is actually not a new phenomenon, nor did it come out of the modern feminist movement. For centuries, women have made choices about limiting births and whether or not to become mo…
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Episode 8 of the Trading Places Pod featuring Phil Haslett from EquityZen is out now. This week we dive deep into OpenAI's massive semiconductor partnership deals ($500B+ across AMD, Broadcom, Nvidia & Oracle), Goldman's billion-dollar acquisition of Industry Ventures, plus emerging IPO opportunities including Tempo's $5B series A and Anysphere's $…
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Episode 9 of the Trading Places Podcast featuring Seedcamp's Reshma Sohoni and Carlos Eduardo Espinal is out now. This week we cover a jam-packed news cycle (prediction markets 📈, Google-Anthropic deal, Oracle's $38B debt raise, Tether's 500M users 🌍) plus an in-depth interview with the legendary Seedcamp co-founders on their pioneering secondary f…
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Episode 7 of the Trading Places Podcast featuring Turner Novak from The Peel Pod and Banana Capital is out now. This week we cover a range of news highlights from a very boisterous week in tech and fundings (Polymarket, Kalshi, Navan IPO, Bitcoin shorts, gold price boom) plus a jam packed [valuation corner] hosted by Practical Venture Capital's GPs…
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What does it mean to see beneath the surface — of the human body, the brain, or even the universe itself? In his new book, The Future of Seeing: How Imaging Is Changing Our World, Prof. Daniel Sodickson of NYU explores the future of imaging: How technology is transforming not just medicine, but our very ways of perceiving the world. With the rise o…
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Few ideas have gripped the public imagination quite like the idea of the “psychopath.” From Hollywood thrillers to true-crime podcasts, popular culture has led us to believe that psychopaths are dangerous and biologically distinct from the rest of us. But what if almost everything we think we know about them is wrong? In this episode, we talk with …
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episode 6 of @+[trading places] feat. our dear friend / VC’s chief graph officer, peter walker of carta—is out now! 00:00 — cold open [ news ] 00:38 — this week’s news 01:34 — triple triple double double = ded ded DED 03:36 — state of the software 2025 report 07:42 — openAI completes tender offer… what now? 09:43 — IPOs Q3 update 11:43 — get ur IPO…
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For decades, neuroscience has promised breakthroughs in treating conditions like depression, schizophrenia, and Alzheimer’s. Yet despite powerful technologies and billions invested, progress has been frustratingly slow. Why? On this episode of Big Brains, we talk with Nicole Rust, neuroscientist at the University of Pennsylvania and author of Elusi…
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episode 5 of @+[trading places], a very bad 💩podcast about VC #secondary 2️⃣, broken unicorns 🦄💔& busted carry 😱, is out NOW! this week, we sit down with Joe Schorge and Omolade Idebisi of EU fund of funds (FoF) Isomer Capital about secondary fund strategy, GP-led vs. LP-led and how they navigate a world of weird discounts when they go to trade in …
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[ trading places ] episode 4:a very bad 💩podcast about VC #secondary 2️⃣, broken unicorns 🦄💔& busted carry 😱 this week in 2ndry: we talk #SPVs #KYC and #liquidity w/ nik talreja CEO @ sydecar timestamps: [ tech + vc news ] 01:14 — ipo window creaks open (klarna, figma, netskope, stubhub) 07:00 — tiktok deal: oracle, xi, trump 10:16 — fed cuts 25bps…
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Billions of years ago, Mars may have looked less like the barren red desert we know today and more like Earth—with a blue sky, flowing rivers, and even seas. What happened to turn a once-habitable world into the frozen, lifeless planet we see now? On this episode of Big Brains, University of Chicago geophysical scientist Edwin Kite takes us on a jo…
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IPOs are overrated. secondaries are where the bodies get buried. in ep.3 of [trading places], dave mcclure & aman verjee get way too many smart people on one bad pod: emily zheng (pitchbook) — the adult in the room with $61b in us vc secondaries, step-ups, discounts, rofrs, and why ai is the only thing saving your carry. sim desai (hiive) — transpa…
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a very bad podcast about broken unicorns & busted carry in this ep of [trading places], dave mcclure & aman verjee sit down with upfront ventures’ mark suster to talk: * why he sold $600m+ in secondaries before the crash * why vcs are emotionally bad at selling (spoiler: regret math) * how funds fake “long-term conviction” while quietly cashing out…
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We’re living in an attention economy—and most of us are broke. But what if the secret to restoring your focus, improving your mental health, and even reducing crime rates wasn’t found in an app or a pill, but in a tree? In this episode, we speak with University of Chicago psychologist Marc Berman, whose research on “soft fascination” and nature’s c…
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in this inaugural ep of [trading places], dave mcclure & aman verjee welcome david zhou (super clusters) to talk secondary markets, ai bubbles, and why your DPI might be total bs we go deep on: – openai’s $500B tender – canvas vs databricks valuations – LP/GP dynamics – when to sell in secondaries – spv food fights – and the ghost of rap battles pa…
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We’ve long marveled at how efficiently plants convert sunlight into energy—but no one guessed they were using quantum mechanics to do it. In this episode, we speak with Greg Engel, a pioneering biophysicist at the UChicago Pritzker School of Molecular Engineering and the Department of Chemistry who helped launch the field of quantum biology. Engel …
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You’ve heard of plastic polluting oceans. But what if it’s polluting you—your brain, your reproductive system, even your unborn children? In this eye-opening episode, we speak with Prof. Matthew Campen, a scientist at the University of New Mexico, whose latest studies have uncovered evidence of microplastics in placentas, reproductive organs and br…
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Hello listeners…we're re-releasing one of our favorite Big Brains episodes—an incredibly insightful conversation with psychologist Adam Alter. If you've ever felt stuck in your life or career, this episode offers practical strategies and surprising science to help you move forward. From why your best ideas might come after you feel like giving up, …
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One of the benefits of producing this podcast at the University of Chicago is that there are often events on campus that bring in not just one Big Brain, but many in order to find answers to the some of the most complex problems of our time. I recently had the pleasure of hosting one such event on artificial intelligence that we want to share with …
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For a more than a century, the Food and Drug Administration has worked to protect public health. In his research, Harvard University physician-researcher Jerry Avorn has examined how the FDA’s once-rigorous gold standard approval process has been affected by a powerful shortcut known as the Accelerated Approval Program—originally designed for despe…
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Prof. James Evans, a University of Chicago sociologist and data scientist, believes we’re training AI to think too much like humans—and it’s holding science back. In this episode, Evans shares how our current models risk narrowing scientific exploration rather than expanding it, and explains why he’s pushing for AIs that think differently from us—w…
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When someone we know or love starts to develop psychological issues, we don't often associate it with a form of dementia. However, this trait is one of the most common signs of frontotemporal dementia (FTD) — the most common neurodegenerative disease in people under the age of 65. In his new book, Mysteries of the Social Brain: Understanding Human …
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The search for life beyond Earth is no longer science fiction—it takes a lot of data, powerful telescopes and a bit of cosmic detective work. And at the center of this search is University of Chicago astrophysicist Jacob Bean. Bean was part of the team that made history by detecting carbon dioxide in the atmosphere of a distant planet using the Jam…
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Despite decades of policy ideas, pouring millions of dollars into the problem, and a slow pace of gun control measures, the United States hasn’t made much progress on curbing the epidemic of gun violence in our country. For the past 25 years, Prof. Jens Ludwig of the University of Chicago has examined the questions of: Why does gun violence happen,…
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What if a single number, derived from your DNA, could predict your income, education level or even who you're likely to marry? In his new book “The Social Genome,” Princeton University sociologist Dalton Conley explores the science behind how our genes are shaping our society in ways that are both profound and unsettling. Conley explains how our ge…
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In this episode of Start Up Showcase, host Colton Hower sits down with Hannah Samlall, co-founder of both Waterloo Street, a branding and web design agency, and The Biz Collective, a community-driven membership supporting women-owned businesses. Together with her sister Rachel, Hannah has built a thriving creative agency while championing small bus…
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When we lose someone, we love, we often say we have a broken heart—but what if that’s not just a metaphor? In her new book “The Grieving Body: How The Stress of Loss Can Be An Opportunity For Healing” University of Arizona Professor of Psychology Mary Frances O’Connor shares groundbreaking insights into the biological and physiological impacts grie…
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