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Clinician, researcher, and gut-geek Dr. Michael Ruscio DC covers the ever-changing world of functional health science. From debunking trends to research deep dives to practical takeaways, Dr. Ruscio DC Radio is health science made digestible. These [podcasts] are educational and informational only and are not medical, chiropractic, psychological, or other professional advice of any kind. They do not create or constitute any professional relationship between us and you. Always consult your li ...
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- Medication-related osteonecrosis of the jaw (MRONJ) is a serious condition where jawbone dies and fails to heal, and it’s been linked to common bone drugs like bisphosphonates and denosumab
- A Finnish study found that people taking denosumab were five times more likely to develop MRONJ than those using bisphosphonates, with cancer patients and long-term users at highest risk
- Adding corticosteroids to bone drugs significantly worsened outcomes, multiplying the risk of jaw disease by up to six times in some users
- MRONJ often begins after dental procedures like extractions, but it also develops in people with gum disease or dentures — even without dental intervention
- Preventive dental care, a nutrient-rich diet, and lifestyle habits that support natural bone repair offer your best defense against this disfiguring and painful condition
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