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Content provided by Dr. Chris Magryta, "Dr. M", Dr. Chris Magryta, and "Dr. M". All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr. Chris Magryta, "Dr. M", Dr. Chris Magryta, and "Dr. M" or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
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Dr. M’s SPA Newsletter Volume 15 Issue 6

 
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Manage episode 484708778 series 1064617
Content provided by Dr. Chris Magryta, "Dr. M", Dr. Chris Magryta, and "Dr. M". All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr. Chris Magryta, "Dr. M", Dr. Chris Magryta, and "Dr. M" or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
This is such an important topic to cover, even for a pediatrician. Dementia! This problem is slated to exponentially worsen in the coming decades. And it starts at birth! ​In the intricate landscape of Alzheimer's disease (AD), emerging research underscores a pivotal yet under explored facet for the why?, the brain's energy immunometabolism. A recent study by Patel et al., titled "Global Energy Metabolism Deficit in Alzheimer Disease Brain," delves into this domain, revealing significant metabolic disruptions that may illuminate novel upstream causes and possible therapies. ​ For the better part of the last few decades, all AD research centered on the amyloid and tau plaques as the causative problem. However, billions of dollars and many drugs later, this hypothesis has crashed and burned. Failed therapies coupled to the skyrocketing volume of AD patients in the US over the next few decades will burden the US healthcare system and families alike. Folks, we need better answers and therapies rapidly. Thus, I have been following this information on and off over the years looking for answers. Last month, Dr. David Perlmutter gave an excellent lecture on microglial cells in the brain and their impact on AD and neurocognition in general. One paper that he cited was the Patel paper. Let's look at it. Dr. M
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426 episodes

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iconShare
 
Manage episode 484708778 series 1064617
Content provided by Dr. Chris Magryta, "Dr. M", Dr. Chris Magryta, and "Dr. M". All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr. Chris Magryta, "Dr. M", Dr. Chris Magryta, and "Dr. M" or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
This is such an important topic to cover, even for a pediatrician. Dementia! This problem is slated to exponentially worsen in the coming decades. And it starts at birth! ​In the intricate landscape of Alzheimer's disease (AD), emerging research underscores a pivotal yet under explored facet for the why?, the brain's energy immunometabolism. A recent study by Patel et al., titled "Global Energy Metabolism Deficit in Alzheimer Disease Brain," delves into this domain, revealing significant metabolic disruptions that may illuminate novel upstream causes and possible therapies. ​ For the better part of the last few decades, all AD research centered on the amyloid and tau plaques as the causative problem. However, billions of dollars and many drugs later, this hypothesis has crashed and burned. Failed therapies coupled to the skyrocketing volume of AD patients in the US over the next few decades will burden the US healthcare system and families alike. Folks, we need better answers and therapies rapidly. Thus, I have been following this information on and off over the years looking for answers. Last month, Dr. David Perlmutter gave an excellent lecture on microglial cells in the brain and their impact on AD and neurocognition in general. One paper that he cited was the Patel paper. Let's look at it. Dr. M
  continue reading

426 episodes

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