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HBO and The Ringer's Bill Simmons hosts the most downloaded sports podcast of all time, with a rotating crew of celebrities, athletes, and media staples, as well as mainstays like Cousin Sal, Joe House, and a slew of other friends and family members who always happen to be suspiciously available.
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On this episode discuss the side effects of GLP-1 medications like Ozempic and Wegovy, Zepbound, and Mounjaro offering practical strategies to manage these effects while still benefiting from the medications.
• GLP-1 medications (Ozempic, Wegovy, Mounjaro, Zepbound) help manage type 2 diabetes, obesity, and can reduce cardiovascular risk
• Most common side effects are gastrointestinal: nausea, vomiting, diarrhea, bloating, and constipation
• "Sulfur burps" are a frequently reported side effect that some manage with Pepto-Bismol
• Start with low doses and increase slowly to minimize side effects
• Eat smaller portions, avoid greasy/spicy foods, and practice mindful eating to reduce GI symptoms
• Stay hydrated and increase fiber intake to prevent constipation
• Gallbladder problems and pancreatitis risk may increase with rapid weight loss
• Some evidence suggests potential vision changes requiring regular eye check-ups
• Medications like insulin or blood pressure drugs may need adjustment when on GLP-1s
• Most side effects improve with time as your body adjusts to the medication
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Production and Content: Edward Delesky, MD & Nicole Aruffo, RN
Artwork: Olivia Pawlowski
Chapters
1. Welcome and Poop Cruise Recap (00:00:00)
2. Philly Trash Strike Discussion (00:05:42)
3. Kalaya Thai Restaurant Review (00:09:53)
4. GLP-1 Medications Introduction (00:18:40)
5. Managing GLP-1 Side Effects (00:27:12)
6. When to Seek Medical Help (00:38:08)
7. Closing and Disclaimer (00:47:10)
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