Join Dr. Kay and renowned female longevity expert Kayla Barnes for a comprehensive discussion on optimal health, moving far beyond "normal" lab ranges to an optimal state. Kayla breaks down essential longevity strategies, from tailoring sleep and exercise protocols to the female cycle and structuring supplements into three categories (baseline, protocol-based, and longevity molecules), to pursuing advanced testing like NMR panels and Homa IR to decode health data. The episode explores cutting-edge therapies like Hyperbaric Oxygen (HBOT) for enhanced healing and blood flow, and Therapeutic Plasma Exchange (TPE) for reducing the total toxic burden. Finally, Dr. Kay and Kayla align on an approach to aesthetic longevity that advocates for a moderated use of pure core neurotoxins like Xeomin in combination with powerful collagen biostimulation and DNA-repairing molecules, such as polynucleotides, for true inside-out rejuvenation.