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HBO and The Ringer's Bill Simmons hosts the most downloaded sports podcast of all time, with a rotating crew of celebrities, athletes, and media staples, as well as mainstays like Cousin Sal, Joe House, and a slew of other friends and family members who always happen to be suspiciously available.
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In this episode I take questions from the audience and review the research on a variety of topics.
The concussion we all missed: Using Mike Evans’ hit as a case study, Dr. Z shows why a “minor” concussion can be far more life-altering than a broken collarbone—and how symptoms get rationalized away.
Depression redefined: New findings on excitatory neurons and microglia link mood and inflammation—explaining why exercise, vitamin D, gut health, and targeted nutrition help some people more than meds alone.
Women’s brain health & hormones: How menopause accelerates brain atrophy in MS, which regions are hit (memory, attention, emotion), and why LC/MS hormone testing changes the conversation on safe HRT.
Parkinson’s is rising—here’s why: Environmental exposures (industrial degreasers, pesticides, head trauma, autoimmunity) drive risk—and the practical levers you can control now.
From POTS to “wear-and-tear” knees: Why POTS is a neuro-immune problem (not a single-cause diagnosis), how ultra-processed foods speed cartilage loss, and what emerging evidence says about Boswellia + celery seed for pain, function, and inflammation.
27 episodes
