A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health and hosted by Kris Tatiossian and Olivia Webb, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vijay Pande, Julie Yoo, Vineeta Agarwala, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg ...
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Content provided by Cynthia Thurlow and Everyday Wellness™. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Cynthia Thurlow and Everyday Wellness™ or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
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Ep. 468 The Alzheimer’s Research Crisis with Charles Piller
Manage episode 484507718 series 2437481
Content provided by Cynthia Thurlow and Everyday Wellness™. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Cynthia Thurlow and Everyday Wellness™ or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
Today, I am thrilled to connect with Charles Piller, an award-winning investigative journalist for Science magazine whose work has also appeared in The Los Angeles Times, The New York Times, The Sacramento Bee, and other major publications. Charles is the author of Doctored, and he has been honored with several national journalism awards.
In our fascinating conversation, we dive into the trajectory of Alzheimer’s from its early framing as a diagnosis to its modern-day research landscape. We explore the concept of publish or perish within academic research, and we examine the dominant amyloid hypothesis, the forces shaping scientific narratives, and the role of institutions like the FDA, NIH, and research publishing in influencing research priorities. Charles shares his insights on the impact of falsified data and the broader implications for scientific integrity of the doctored images published in Nature in 2006. We also tackle the importance of lifestyle and risk factor modification in preventing neurocognitive decline.
You will not want to miss this compelling conversation with Charles Piller. His book is a gripping must-read on the fraud, arrogance, and tragedy in the quest to cure Alzheimer’s.
IN THIS EPISODE, YOU WILL LEARN:
How Alzheimer’s impacts our society and affects the caregivers of those with Alzheimer’s
Charles gives a historical overview of Alzheimer's
Some typical symptoms of Alzheimer's
How the amyloid cascade hypothesis led to the development of drugs that removed amyloid from the brain but failed to halt or reverse dementia
How doctored images can support experimental hypotheses and influence research
Charles highlights the need for more accountability within the scientific field.
How pressure to publish and perverse incentives have influenced Alzheimer’s research
Why ethical concerns matter when developing potentially hazardous drugs with limited benefits
Charles shares the potential benefits of GLP-1s for cognitive decline.
Why a multi-factorial approach to understanding and treating Alzheimer's is essential
Charles highlights the importance of self-criticism and humility within the scientific community.
Connect with Cynthia Thurlow
Check out Cynthia’s website
Submit your questions to [email protected]
Connect with Charles Piller
On his website
527 episodes
Share
Manage episode 484507718 series 2437481
Content provided by Cynthia Thurlow and Everyday Wellness™. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Cynthia Thurlow and Everyday Wellness™ or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
Today, I am thrilled to connect with Charles Piller, an award-winning investigative journalist for Science magazine whose work has also appeared in The Los Angeles Times, The New York Times, The Sacramento Bee, and other major publications. Charles is the author of Doctored, and he has been honored with several national journalism awards.
In our fascinating conversation, we dive into the trajectory of Alzheimer’s from its early framing as a diagnosis to its modern-day research landscape. We explore the concept of publish or perish within academic research, and we examine the dominant amyloid hypothesis, the forces shaping scientific narratives, and the role of institutions like the FDA, NIH, and research publishing in influencing research priorities. Charles shares his insights on the impact of falsified data and the broader implications for scientific integrity of the doctored images published in Nature in 2006. We also tackle the importance of lifestyle and risk factor modification in preventing neurocognitive decline.
You will not want to miss this compelling conversation with Charles Piller. His book is a gripping must-read on the fraud, arrogance, and tragedy in the quest to cure Alzheimer’s.
IN THIS EPISODE, YOU WILL LEARN:
How Alzheimer’s impacts our society and affects the caregivers of those with Alzheimer’s
Charles gives a historical overview of Alzheimer's
Some typical symptoms of Alzheimer's
How the amyloid cascade hypothesis led to the development of drugs that removed amyloid from the brain but failed to halt or reverse dementia
How doctored images can support experimental hypotheses and influence research
Charles highlights the need for more accountability within the scientific field.
How pressure to publish and perverse incentives have influenced Alzheimer’s research
Why ethical concerns matter when developing potentially hazardous drugs with limited benefits
Charles shares the potential benefits of GLP-1s for cognitive decline.
Why a multi-factorial approach to understanding and treating Alzheimer's is essential
Charles highlights the importance of self-criticism and humility within the scientific community.
Connect with Cynthia Thurlow
Check out Cynthia’s website
Submit your questions to [email protected]
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On his website
527 episodes
All episodes
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Similar to Everyday Wellness with Cynthia Thurlow ™
A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health and hosted by Kris Tatiossian and Olivia Webb, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vijay Pande, Julie Yoo, Vineeta Agarwala, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg ...
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continue reading
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…
continue reading
This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.
…
continue reading
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…
continue reading
The BMJ brings you interviews with the people who are shaping medicine and science around the world.
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continue reading
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