When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years – sometimes decades – earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimer’s disease. Perhaps you have a family member with Alzheimer’s disease, or ca ...
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Methotrexate is a well-established drug used in oncology, but could it also play a role in managing osteoarthritis? In this episode of Joint Action, Professor David Hunter is joined by Dr Anna Døssing and Professor Robin Christensen to explore the potential of methotrexate as a treatment for osteoarthritis pain.
They discuss:
- What methotrexate is and how it works
- Insights from a recent meta-analysis on its effectiveness and safety
- Why individual studies show mixed results
- Whether it might help people with hand or knee OA - especially those with signs of inflammation
- How dosing and side effects factor into clinical decision-making
Tune in for an honest, data-driven conversation about repurposing an old drug for a new purpose - and what it could mean for people living with osteoarthritis.
RESOURCES
- Editorial: Methotrexate for osteoarthritis—Ready for clinical use and in whom?: https://www.oarsijournal.com/article/S1063-4584(25)00973-2/abstract?
CONNECT WITH US
- Twitter: @ProfDavidHunter @jointactionorg
- Instagram: @osteoarthritisresearchgroup
- Email: [email protected]
- Website: https://www.jointaction.info/podcast
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155 episodes