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EP Edge Journal Watch

Niraj Sharma MD FACC FHRS

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Welcome to EP Edge Journal Watch — where cardiac electrophysiology meets evidence, precision, and perspective. Hosted by Dr. Niraj Sharma, this bi-weekly podcast distills high-impact cardiovascular and EP research into clear, clinically meaningful insights. Each episode goes beyond headlines and abstracts to uncover what new studies actually mean for patient care, decision-making, and the future of electrophysiology. What EP Edge Journal Watch stands for: Evidence-based practice Precision el ...
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EP Edge

Niraj Sharma MD FACC FHRS

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EP-EDGE brings you the latest in cardiac electrophysiology — from breakthrough research and clinical insights to future-shaping innovations. Hosted by Dr. Niraj Sharma, an electrophysiologist with over 15 years of experience, each episode delivers clear, evidence-based updates designed to inform, inspire, and elevate your practice.
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The Pulse Report with Dr. Shen

The Pulse Report with Dr. Shen

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The Pulse Report with Dr. Shen makes heart health clear, practical, and personal. In just 5–10 minutes, each episode distills complex research with clarity and depth, explores innovations in heart care, and tackles common questions and myths. You’ll also hear behind-the-scenes stories from life as a cardiologist, practical skills for everyday heart health, and conversations that remind us every heartbeat carries meaning. Whether you’re living with a heart condition, supporting someone you lo ...
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Back to Health

Weill Cornell Medicine

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Back To Health is your source for the latest in health, wellness and medical care for the whole family. Our team of world-renowned physicians at Weill Cornell Medicine, are having in-depth conversations covering trending health topics, wellness tips and medical breakthroughs here on Back to Health. We understand that medicine is complex and can be overwhelming, that’s why we’ve developed this podcast as a resource for you, your loved ones and our community. We believe that knowledge is empow ...
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Smartwatches are now among the most widely used heart-monitoring tools in the world — but how accurate are they really at detecting AFib? In this December 2025 Issue 3 of EP-Edge Journal Watch, Dr. Niraj Sharma, cardiologist and cardiac electrophysiologist, breaks down the strongest evidence to date on smartwatch AFib detection, Apple Watch ECG per…
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In this issue, we trace the fascinating evolution of atrial fibrillation (AF) therapy — from the Cox Maze procedure to Haïssaguerre’s discovery of pulmonary vein ectopy, through Pappone’s wide antral isolation, and onward to the era of pulse field ablation (PFA). We explore how ablation technologies have transformed — radiofrequency, cryo, and PFA …
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Dr. Alexandra King discusses the latest advancements in women's health screening guidelines. She goes over the updates for cervical and breast cancer screenings, as well as insightful recommendations for managing bacterial vaginosis and changes in menopause. She shares insights on the evolving landscape of women's wellness and why these changes mat…
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In this special EP Edge Journal Watch episode, Dr. Niraj Sharma delivers a critical analysis of the landmark AQUATIC Trial, published in the New England Journal of Medicine (October 2025). This pivotal study explores optimal antithrombotic strategies in patients with atrial fibrillation (AF) and coronary artery disease (CAD) — balancing ischemic pr…
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In this episode, Dr. Niraj Sharma breaks down six pivotal studies shaping today’s electrophysiology and cardiology practice—from lifestyle-driven AF control (ARREST-AF) and post-CABG atrial fibrillation management to the DOAC + aspirin conundrum in stable CAD, the return of digitoxin in HFrEF, insights from CABANA-Substudy, and the latest ICD regis…
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In this inaugural episode, Dr. Niraj Sharma breaks down three pivotal studies that could shift daily EP practice: How high-normal potassium targeting can reduce VT burden (POT-CAST trial). When GDMT withdrawal may be safe after recovery from tachycardia-induced cardiomyopathy. Why adverse pregnancy outcomes may predict long-term AF risk. Get the si…
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Dr. Susan Loeb-Zeitlin discusses the essential lifestyle changes that can help women in midlife embrace a healthier, happier life. She highlights how nutrition, exercise, and mental well-being play a crucial role in maintaining vitality during midlife and beyond. She provides an overview on the importance of preventive healthcare, routine screening…
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What if stroke prevention in atrial fibrillation no longer meant trading protection for bleeding risk? Factor XI inhibition—led by trials like AZALEA–TIMI 71, LILAC–TIMI 76, and LIBREXIA–AF—is poised to rewrite the anticoagulation playbook. By targeting the intrinsic pathway, these agents may decouple thromboembolic protection from major bleeding, …
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The paradigm is shifting. Ventricular tachycardia (VT) ablation is stepping out of the shadows—from rescue therapy to first-line strategy, driven by landmark trials like VANISH2, PAUSE-SCD, and PARTITA. Meanwhile, pulse field ablation (PFA) continues its rapid evolution—crossing over from atrial to ventricular applications—but questions about durab…
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Left atrial appendage occlusion (LAAO) has evolved from a niche option for oral anticoagulation–intolerant patients to a frontline procedural strategy for stroke prevention in atrial fibrillation. Landmark trials like OPTION, SWISS‑APERO, and COMBINATION are redefining how and when we use these devices. In this episode of EP Edge, Dr. Niraj Sharma …
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Pulse field ablation (PFA) has been hailed as the next frontier in atrial fibrillation therapy—nonthermal, ultra-selective, and lightning fast. But as new data emerges, important questions are rising about its systemic effects, cerebral safety, and vascular complications. In this episode of EP Edge, Dr. Niraj Sharma unpacks the latest findings from…
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Ablation is powerful—but lifestyle is transformative. As atrial fibrillation (AF) continues to rise globally, emerging evidence makes it clear: lifestyle modification is not just complementary care, it’s frontline therapy. In this episode of EP Edge, Dr. Niraj Sharma explores how structured lifestyle interventions—targeting weight, alcohol use, sle…
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In this episode of EP Edge Podcast, Dr. Niraj Sharma dives deep into the clinical promise and procedural realities of LBBAP: Clinical advantages: improved LVEF, narrower QRS, lower VT/VF and AF incidence. RV protection: reduced risk of pacing-induced cardiomyopathy. Sex-specific outcomes: women with NICM + LBBB derive greater benefit. Complications…
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Dr. Magdalena Lombardi Plasilova discusses the groundbreaking impact of artificial intelligence (AI) in breast cancer diagnosis and treatments. She highlights how AI assists doctors in many ways, including interpreting mammograms and identifying suspicious lesions. She reviews issues concerning bias in AI algorithms and datasets when used in health…
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Atrial fibrillation (AFib) isn’t just disruptive — it can affect daily life, raise stroke risk, and lead to long-term complications. In this episode of The Pulse Report, Dr. Shen, a cardiologist specializing in electrophysiology and the Director of Research and Education at Cardiovascular Medicine (CVM), takes you inside one of the most exciting ad…
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For people living with atrial fibrillation (AFib), one of the greatest concerns is the risk of stroke. Traditionally, that risk is managed with blood thinners such as Eliquis, Xarelto, or Warfarin. More recently, the WATCHMAN device has provided another option, sealing off the left atrial appendage where most clots form. Now, a major international …
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Living with atrial fibrillation (AFib) means more than coping with an erratic heartbeat—it means facing the twin challenges of maintaining rhythm and avoiding stroke. In this Innovation Update from The Pulse Report, Dr. Shen, a cardiologist specializing in electrophysiology and the Director of Research and Education at Cardiovascular Medicine (CVM)…
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Atrial fibrillation (AFib) isn’t just about irregular heartbeats—it also has important implications for brain health. In this episode of The Pulse Report, Dr. Shen, a cardiologist specializing in electrophysiology and the Director of Research and Education at Cardiovascular Medicine (CVM), breaks down findings from a major international study publi…
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Dr. Michelle Loy discusses integrative health and lifestyle medicine for women through the life stages. She emphasizes the importance of seeking evidence-based care to best address holistic wellness. She provides insights on preventive care and how integrative medicine can assist in navigating these changes as women age. Learn more about Michelle L…
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Dr. Fahey discusses pulsed field ablation, a minimally invasive procedure used in removing benign thyroid nodules. He discusses the effectiveness and benefits of the innovative treatment for select candidates looking to address thyroid issues. He highlights the shared decision-making process that patients should partner with their healthcare provid…
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Dr. Elizabeth Anne Grill discusses the emotional journey that couples can experience during infertility. She offers invaluable insights on coping strategies that foster emotional resilience when feelings of grief, anger, and despair arise. She also delves into actionable advice for friends, family, and partners to provide the empathic support that …
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Dr. Bob Harrington discusses the importance of heart-healthy living through the life stages. He highlights the recent alarming statistics around cardiovascular diseases and its prevalence between men and women. He reviews the latest advancements in treating heart health and how Weill Cornell Medicine is leveraging unique technology and innovations …
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Dr. Georges Sylvestre highlights guidance for breast cancer screenings for pregnant and postpartum patients. He discusses recent increased occurrences of the cancer in women under 40 and contributing risk factors, like obesity. He gives an overview of recommended ways of detecting the cancer including for patients to know their breasts by recognizi…
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Dr. Kristen de Vries discusses what patients should know about cancer rehabilitation medicine. At Weill Cornell Medicine, our cancer rehabilitation specialists aim to improve patients’ quality of life using a holistic, empathetic and patient-centric approach. We use holistic cancer treatments, also called complementary or alternative cancer treatme…
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Dr. Mariam Ashraf discusses what patients should know about detecting, preventing and treating sports-related injuries. She reviews the common types patients come in for and what can cause issues, like chronic over-use or compounded stress on muscles and joints. She highlights the importance of stretching and warming up before playing sports. She a…
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Dr. Tiffany Lin discusses what patients should know about Botox treatment for headaches and migraine. She describes how the procedure works by reducing the release of neurotransmitters and proteins that cause triggering inflammation and pain. She highlights the low side effects of the quarterly injections, as compared to other daily dose regiments,…
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Dr. Jaspal R. Singh discusses what patients should know about training and running marathons. He also highlights the importance of recovery after running long distances. He goes over the importance of being physically and mentally prepared in advance of running a marathon and how runners should start preparing 4-5 months before a race. He gives adv…
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Today's special episode of Back to Health comes from On the Mind, the official podcast from the Weill Cornell Medicine Department of Psychiatry. In this special election year episode, host Dr. Daniel Knoepflmacher engages with Dr. Richard Friedman to explore the psychological toll of contemporary American politics. They discuss how polarization, un…
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Dr. Moises Dominguez discusses what patients should know about chronic migraine. He shares the differences between episodic and chronic migraines, including the frequencies of occurrences of the latter type. He reviews how the migraine can be disabling and debilitating for people experiencing them. He also highlights the importance of shared decisi…
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Dr. Jai S. Perumal discusses what patients should know about available treatments for primary progressive multiple sclerosis (PPMS). She reviews how the symptoms of inflammation outside of the brain develop gradually and the rates of occurrence between men and women. She highlights how early intervention to prevent further damage and the comprehens…
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Dr. Jai S. Perumal discusses what patients should know about lifestyle changes for managing Multiple Sclerosis (MS). She highlights the benefits of eating a healthy diet, plus supplements like vitamin D and B12, in alleviating symptoms of MS. She also notes that diet is personal but MS patients should avoid foods that could trigger inflammation or …
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Dr. Daniel Pak discusses what patients should know about sciatica. He describes how the condition can be caused by herniated disc and its impacts to the sciatic nerves down the lower back into the legs. He reviews the available treatments including injections, physical therapy, and potentially surgery. He highlights the collaborative approach to ca…
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Dr. Rohan Jotwani discusses what patients should know about managing pain or discomfort while working from home. He gives advice on optimizing the ergonomics within one's home office, which can help with preventing issues of tech neck and carpal tunnel. He reviews the preventative exercises one can use while working at home and highlights the inter…
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We’re so glad you joined us for this special episode of "Women's Health Wednesday.” We hope you'll tune in and become part of a community--and a fast-growing audience--of women looking for knowledge, insight, and real answers to hard questions about our bodies and our health. Please download, subscribe, rate and review Back To Health on Apple Podca…
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Dr. Michael Ethan Stern and Alyssa Elman, LCSW discuss the what patients should know about preventing elder abuse and mistreatment. They highlight the Vulnerable Elder Protection Team (VEPT) and their 24/7 services in protecting vulnerable adults. VEPT is a first-of-its-kind Emergency Department (ED) / hospital-based multi-disciplinary team that ad…
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In this special episode from On the Mind, Dr. Daniel Knoepflmacher explores the complexities of women's mental health during hormonal transitions with Lauren Osborne, M.D. and Alison Hermann, M.D. The conversation focuses on mental health throughout the various stages of life and hormonal changes. Discover the underlying factors influencing women's…
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Dr. Larissa Rodriguez discusses what patients should know about pelvic and bladder health through the life stages. She provides an overview of the symptoms of pelvic or fecal incontinence and how they may impact a woman's quality of life. She encourages women to not feel alone and to not feel embarrassed to discuss with their doctors if they're exp…
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Dr. Robert McInnis discusses the latest novel treatments for seizures and epilepsy. He gives an overview of the causes that may lead to developing seizures and epilepsy. He reviews the role of food, like the ketogenic diet, which can help to control the instances of seizure episodes and how anti-epileptic drugs that can be used for prevention. Fina…
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Dr. Rajiv Magge discusses the latest in research and treatments for brain tumors. He gives an overview of primary and metastatic types of brain tumors and how uncommon they are for most patients. He highlights common symptoms and when patients should seek an evaluation by a neurologist. He gives an update on the latest breakthroughs treatments for …
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Dr. Daniel Barone discusses how seasonal changes can impact sleep. He goes over common sleep issues and problems that can impact patients when daylight savings time changes. He highlights the importance of consistent schedules and gives tips on healthy sleep routines. He also recommends sleep evaluations should issues persist year around. To schedu…
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Dr. Mohammad Piracha discusses what patients should know about treating and managing diabetic nerve pain. He speaks on the prevalence of diabetes and multifactorial impacts of the condition across the country and globally. He shares on how diabetic neuropathy and how it can impact distal nerves and regulation of the autonomic system. He goes over h…
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Dr. Mehraneh Jafari shares what patients should know about healthy eating guidelines for candidates of colon and rectal surgery. She provides dietary recommendations ahead of surgery, especially to help with prep and recovery for after the surgical procedures. She highlights the importance of developing healthy eating habits by incorporating more p…
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Dr. Philip Petrou discusses what patients should know about body aches during the cold season. He highlights how the change in barometer pressure could impact joint pain and swelling of blood vessels. He gives recommendations for managing the acute pain, like staying active indoors, keeping warm by wearing layers and utilizing heat therapy. He also…
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Dr. Andrea Yoo discusses what patients should know about dystonia. She describes the conditions of the movement disorder that causes involuntarily contractions of muscles. While there is currently no cure, she reviews the helpful treatments available to alleviate painful symptoms. To schedule with Dr. Andrea Yoo…
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Anyanate Gwendolyne Jack, M.D. and Rachel Stahl Salzman, M.S. discuss what patients should know about the recent advancements in obesity and diabetes management. The panel discusses the ongoing rise in cases for obesity, pre-diabetes and diabetes. They review risk factors and behaviors can lead to obesity, as well as addressing systemic issues that…
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