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We trace an eight-stage cascade showing how meaning turns into chemistry, gene expression, protein shifts, and long-term health. We share evidence from stress science and epigenetics and close with tools that let you edit the script.
• early-life context shaping the epigenome
• cognitive appraisal connecting belief to meaning
• emotional circuits and neurochemical blends
• HPA axis dynamics and cortisol costs
• epigenetic switches adjusting gene accessibility
• protein-level changes including BDNF and cytokines
• system-wide effects on immunity, mood, and metabolism
• practical interventions to reframe, calm, and recalibrate
This podcast is created by Ai for educational and entertainment purposes only and does not constitute professional medical or health advice. Please talk to your healthcare team for medical advice.

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Chapters

1. From Beliefs To Biology (00:00:00)

2. Early Life And The Epigenome (00:00:35)

3. Cognitive Appraisal Sets Meaning (00:02:11)

4. Emotions And Neurochemistry (00:03:10)

5. The HPA Axis And Cortisol (00:04:16)

6. Epigenetics: Turning Genes Up Or Down (00:05:20)

7. Proteins, Plasticity, And Inflammation (00:06:32)

8. Health Outcomes And How To Intervene (00:07:15)

9. Rapid Recap And Final Question (00:11:20)

82 episodes