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We trace how the gut–brain axis shapes mood, memory, and focus through neural, hormonal, and immune signaling, and why 90% gut-made serotonin reframes mental health. We close with practical steps to grow microbial diversity and cut inflammation through diet.
• Definition of the gut–brain axis and bidirectional signaling
• Roles of the vagus nerve, endocrine hormones, and immune cues
• Microbial metabolites including SCFAs, GABA, and serotonin dynamics
• Barrier integrity, leaky gut, and neuroinflammation links
• Stress as a fast disruptor of microbiome and barriers
• Associations with depression, anxiety, autism, and Alzheimer’s
• Evidence from probiotics and the SMILES Mediterranean diet trial
• Practical tools: 30 plants per week, fermented foods, less ultra-processed intake
• Probiotic strains with emerging support: Lactobacillus rhamnosus, Bifidobacterium longum
• Core takeaway: feed the gut to fuel the mind
This podcast is created by Ai for educational and entertainment purposes only and does not constitute professional medical or health advice. Please talk to your healthcare team for medical advice.

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