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This episode examines a comprehensive narrative review analyzing fasting's profound effects on metabolic hormones and functions across 13 different studies and fasting protocols. Dr. Scott and Tommy reveal a game-changing mental approach: shift from counting down your fasting timer to counting up the powerful benefits accumulating in your body during each fast. The research demonstrates remarkable results from consistent intermittent fasting practices - 24-hour fasts performed three times weekly in women produced increased antioxidant activity, weight reduction, improved morning glucose levels, better A1C readings, and significant improvements in blood pressure, cholesterol, and triglycerides. Learn how 16:8 time-restricted eating for 12 weeks dramatically enhanced multiple metabolic markers in patients with metabolic syndrome, while understanding the crucial differences between fasting effects in lean individuals versus those with excess weight. The hosts clarify testosterone concerns, explaining why lean men may see temporary decreases with extended fasting protocols (typically due to inadvertent under-eating) while overweight men experience increases through improved testicular function and reduced estrogen conversion. Discover practical strategies for building sustainable fasting habits through progressive skill development rather than perfectionist approaches, including proper electrolyte management, leveraging gut microbiome improvements, and strategic meal planning for optimal fast-breaking. This episode reframes fasting as a learnable skill requiring practice and adaptation, providing specific guidance for developing your personal fasting toolkit based on your health status, body composition, and long-term metabolic optimization goals.

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Article Links: https://pmc.ncbi.nlm.nih.gov/articles/PMC11560338/pdf/2188-2126-70-5-0348.pdf