In today's episode, Dr. Scott Watier and Tommy Welling break down a groundbreaking 2025 systematic review examining intermittent fasting's impact on cardiovascular disease prevention, revealing how modified alternate day fasting and time-restricted eating outperform traditional calorie restriction for reducing blood pressure, blood sugar, and waist circumference. They explore the practical application of "fast cycling"—strategically combining daily 16-18 hour fasts with weekly 24-48 hour extended fasts—to maximize both adherence and metabolic benefits without feeling deprived. The hosts emphasize that these research findings reflect the power of fasting timing itself, independent of strict dietary rules, making this approach more sustainable than traditional dieting. They provide actionable guidance on establishing a consistent fasting baseline while incorporating periodic extended fasts to leverage the cardiometabolic advantages seen in the research. Whether you're looking to prevent cardiovascular disease, break through a weight loss plateau, or simply establish a maintainable fasting lifestyle, this episode delivers the evidence-based framework and practical strategies to make fasting work for your long-term health goals.

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Article Links:

https://pmc.ncbi.nlm.nih.gov/articles/PMC12289860/pdf/13668_2025_Article_684.pdf