In this research-driven episode, Dr. Scott Watier and Tommy Welling break down a comprehensive meta-analysis comparing multiple intermittent fasting protocols, revealing what actually works for sustainable weight loss and metabolic health improvement. They examine alternate day fasting, 5:2 fasting, and time-restricted eating, comparing outcomes for weight loss, cholesterol improvements, insulin resistance reduction, and long-term adherence rates. The hosts deliver crucial perspective on the trade-offs between aggressive protocols that produce faster results versus sustainable baseline approaches that support consistency through life's challenges. With the holiday season in full swing between Thanksgiving and Christmas, they provide a realistic framework for maintaining progress without perfectionism or all-or-nothing thinking. This episode helps you understand why chasing the fastest results often backfires, how to customize fasting protocols to match your lifestyle, and why taking the pressure off during the holidays—while maintaining a simple 16:8 baseline—can actually set you up for greater long-term success than aggressive restriction followed by complete abandonment of your fasting practice.

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Article Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC12309044/pdf/12937_2025_Article_1178.pdf